Protein crystallization at the SER-CAT beamline at Argonne’s Advanced Photon Source proved key to the discovery of a new HIV vaccine candidate.
Enhancement of HIV-1 Infectivity. Early work on this topic ... protein other than CD4 that blocks the function of Env in the virion. Nef enhances infectivity by downregulating this unknown protein ...
These valuable findings lay the groundwork for additional studies examining the mechanisms and consequences of this Vif-dependent phenotype in the viral life cycle and in primary cells more relevant ...
Herpesvirus-encoded microRNAs (v-miRNAs) play a crucial role in modulating host cellular processes to promote viral persistence, immune evasion, and pathogenesis. These v-miRNAs function by targeting ...
An innovative dually fluorescent viral platform combining lipophilic dyes staining viral membrane, and a cleavable GFP-Gag chimeric protein as a fluid-phase marker present inside the virion was ...
An effective HIV-1 vaccine must therefore elicit antibodies that can neutralize many variants of the virus. While broadly neutralizing antibodies (bnAbs) have been isolated from HIV-1 infected ...
After a lifetime on the frontiers of the fight against HIV, Linda-Gail Bekker could finally see the end of the epidemic in sight. For decades, HIV experts had dreamed of an elusive vaccine to ...
Two-year-old Evans was brought to the Nyumbani Children’s Home in Nairobi, Kenya a year ago, suffering from HIV and tuberculosis. With no family to care for him, Evans was referred to the ...
The BBC was reporting on a trial vaccine that contained an HIV protein, not the virus itself, and which was never rolled out to the public. A viral Facebook post claims that a video shows how the BBC ...
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