The DNA sequence of rabies virus glycoprotein was used as a vaccine antigen. The sequence was encapsulated into lipid nanoparticles to create the mRNA-based vaccine candidate.

Rabies virus; Lagos bat virus; Mokola virus; Duvenhage virus; ... The genome encodes five genes, nucleoprotein, phosphoprotein, matrix protein, glycoprotein and viral RNA polymerase.

The wild rabies virus has no DNA to manipulate, however, only RNA. The advent of reverse genetics, which flips the normal genetic cycle by making RNA from DNA, got around that hurdle.

A DNA or RNA vaccine, on the other hand, takes a small part of the virus' own genetic information — just enough to spark an immune response — and the protein can be produced directly at the cell.

In the case of rabies, that material is RNA, not DNA. Any rabies virus, and there are several variants, can cause the disease in any mammal.

Influenza, SARS, Ebola, HIV, the common cold. All of us are quite familiar with these names. They are viruses—a little bit of genetic material (DNA or RNA) encapsulated in a protein coat.

Furthermore, a virus genome (the entire complement of DNA or RNA) can permanently colonize its host, adding viral genes to host lineages and ultimately becoming a critical part of the host species ...

Rabies is an acute progressive encephalitis caused by RNA viruses in the family Rhabdoviridae, genus lyssavirus. 11–14 Rabies virus is the only known lyssavirus in the New World. Some locations ...

Scientists develop novel RNA- or DNA-based substances to protect plants from viruses. ScienceDaily . Retrieved June 2, 2025 from www.sciencedaily.com / releases / 2024 / 02 / 240229124622.htm ...

RNA viruses are rapidly emerging as extraordinarily promising agents for oncolytic virotherapy. Integral to the lifecycles of all RNA viruses is the formation of double-stranded RNA, which ...