Clemson is coming off a much-needed 24-10 win over Florida State that ended a long home drought against Power 4 opponents. Louisville, on the other hand, is looking to bounce back from a stunning overtime loss to Cal, a game the Cardinals were heavily favored to win.

After a devastating overtime loss to Cal over the weekend, No. 19 Louisville will look to get back on track against Clemson.

Nov 2, 2024; Clemson, South Carolina, USA; Louisville Cardinals running back Isaac Brown (25) runs the ball against Clemson Tigers cornerback Jeadyn Lukus (10) during the second quarter at Memorial Stadium. Mandatory Credit: Ken Ruinard-Imagn Images / Ken Ruinard / USA TODAY NETWORK via Imagn Images

After the Tigers’ 24-10 victory over Florida State, Swinney opened his postgame remarks by crediting the home crowd for bringing back the energy that’s made Clemson such a tough place to play. He described the scene as “special,” saying night games in the Valley simply don’t get any better when the team and fans feed off each other.

Short week. Short press conference. Jeff Brohm met with the media Monday morning, still stung by Louisville’s overtime loss to California, but with little time to

The Cardinals' head coach, running backs coach, Jordan Guerad and Keyjuan Brown met with the media to discuss their upcoming matchup vs. the Tigers.

BetMGM College Football Odds Opening Line: Clemson by 6.5. Against the spread: Clemson 2-6, Louisville 3-5. Louisville is 72nd in third down percentage, converting 39.8% of the time. Clemson ranks 18th on defense, allowing its opponents at convert at 32.5%.