Background The diagnosis and management of pneumonia is often challenging due to its overlapping clinical presentations with ...

Background Pulmonary hypertension (PH) is a progressive cardiopulmonary condition associated with increased morbidity and ...

Introduction In Hong Kong, tuberculin skin test (TST) with a 15 mm cut-off was used at 0 and 3 months for contact screening, but half of future tuberculosis cases might be missed. Follow-on interferon ...

Lung cancer screening (LCS) with low-dose CT has been proven to reduce lung cancer-specific mortality in high-risk individuals. However, there has been a lot of concern regarding false-positive scans ...

Background Owing to discrepancies in methodologies and how idiopathic pulmonary fibrosis (IPF) is diagnosed it is challenging to establish a consistent understanding of the disease burden In the UK, ...

Contributors EBH-K and SC participated in manuscript writing. All authors approved the final manuscript. SC is the guarantor ...

Correspondence to Professor Michael J Abramson, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC 3004, Australia; michael.abramson{at}monash.edu Introduction ...

Guidelines have been compiled by The Joint Tuberculosis Committee of the British Thoracic Society to quantify the risks of reactivation of tuberculosis with anti-tumour necrosis factor α (anti-TNF-α) ...

3 The University of Manchester, Manchester Academic Health Science Centre, University Hospital South Manchester NHS Foundation Trust, Manchester, UK 4 University Hospital of South Manchester, ...

Introduction The PiSZ genotype results in less severe deficiency of alpha-1 antitrypsin (AAT) than PiZZ. Less is known about phenotypic and prognostic features. Methods We studied 699 PiZZ, 126 PiSZ ...

Introduction Identifying acute hypercapnic respiratory failure is crucial in the initial management of acute exacerbations of COPD. Guidelines recommend obtaining arterial blood samples but these are ...