BACKGROUND: The inability to augment regional cerebral blood flow (CBF) in the setting of steno-occlusive disease involving large brain supplying arteries is a risk factor for stroke. The gold ...

BACKGROUND: Abdominal aortic aneurysm (AAA) is a life-threatening vascular disease with no effective pharmacological treatments. The causal role of triglycerides (TGs) in AAA development remains ...

Role of Passive Leg Raise Stress Echocardiography in Latent Stiff Left Atrial Syndrome ...

Pibarot P, Herrmann HC, Wu C, Hahn RT, Otto CM, Abbas AE, Chambers J, Dweck MR, Leipsic JA, Simonato M, et al; Heart Valve Collaboratory. Standardized definitions for bioprosthetic valve dysfunction ...

Heart failure with preserved ejection fraction (HFpEF) is a multifaceted syndrome with high morbidity and mortality. Empagliflozin, an SGLT2 (sodium–glucose cotransporter 2) inhibitor, reduces adverse ...

Pulmonary hypertension (PH) is a critical disease causing right ventricular failure and early death. Conventional single‐pathway treatments are inadequate, highlighting the need for new therapies.

Time-restricted feeding (TRF), a type of intermittent fasting, has been shown to improve blood pressure; however, there is limited data on its effects in salt-sensitive (SS) hypertension. We ...

BACKGROUND: Myocardial ischemia-reperfusion (I/R) injury induces myocardial fibrosis that compromises cardiac function and electrical conduction, yet current clinical options remain inadequate. To ...

Our results demonstrate that myeloid cell–intrinsic STING signaling is a key driver in DVT progression. STING inhibition, either through specific inhibitors or genetic depletion of myeloid-specific ...