Cochrane | Trusted evidence. Informed decisions. Better health.
WEBCochrane Iran: A beacon of reliable health information in the Middle East. 2 August 2024. News. Global Evidence Summit 2024: Explore Prague while supporting women in leadership. 1 August 2024. News. Cochrane is a global independent network of researchers, professionals, patients, carers and people interested in health.
Which approaches help with recovery after a broken ankle in …
WEBKey messages. - Putting weight on a broken ankle within three weeks of surgery could improve recovery. But it might not improve recovery enough to matter. - Using a removable ankle support (which allows someone to stretch and exercise their injured ankle) during the first six weeks after surgery may improve recovery.
Duloxetine for treating painful neuropathy, chronic pain or
WEBThe usual dose of duloxetine is 60 mg. At this dose, there was moderate quality evidence that duloxetine reduced pain in both painful diabetic peripheral neuropathy and fibromyalgia. In diabetic peripheral neuropathic pain, a 50% or better improvement with duloxetine 60 mg per day was just over one and a half times more likely than with placebo.
Oral painkillers available without prescription for acute pain
WEBNon-prescription (over-the-counter, or OTC) analgesics (painkillers) are used frequently. They are available in various brands, package sizes, formulations, and dose. They can be used for a range of different types of pain, but this overview reports on how well they work for acute pain (pain of short duration, usually with rapid onset).
Which anticholinergic drug for overactive bladder symptoms
WEBThe review found that there are several anticholinergic drugs prescribed for adults with overactive bladder symptoms. The two most studied drugs are oxybutynin and tolterodine. These two drugs have similar effects but, on average, those taking oxybutynin were more likely to withdraw from the studies because of adverse effects, mainly dry mouth.
What are systematic reviews? - Cochrane
WEBCochrane evidence, including our systematic reviews, provides a powerful tool to enhance your healthcare knowledge and decision making. This video from Cochrane Sweden explains a bit about how we create health evidence and what Cochrane does. Search our Plain Language Summaries of health evidence. Learn more about Cochrane and our work.
Gabapentin for chronic neuropathic pain in adults | Cochrane
WEBGabapentin at doses of 1800 mg to 3600 mg daily (1200 mg to 3600 mg gabapentin encarbil) can provide good levels of pain relief to some people with postherpetic neuralgia and peripheral diabetic neuropathy. Evidence for other types of neuropathic pain is very limited. The outcome of at least 50% pain intensity reduction is regarded as a useful ...
Cochrane review of COVID-19 vaccines shows they are effective
WEBDec 7, 2022 · Most trials were no longer than two months in length. The review found that the following vaccines reduced or probably reduced the risk of COVID-19 infection compared to placebo: Pfizer/BioNTech, Moderna, CureVac COVID-19, Oxford-AstraZeneca, Janssen, Sputnik V (Gam-COVID-Vac), Sinopharm (WIBP CorV and …
Bupropion for attention deficit hyperactivity disorder (ADHD
WEBBupropion may be an alternative treatment for adults with ADHD who cannot or will not take stimulant drugs. Quality of the evidence. The quality of the evidence in this review is low, because we found very few studies; five of the six studies were small, and all were poorly conducted. The effect of bupropion on various aspects of daily ...
Latest Cochrane Review finds high certainty evidence that nicotine …
WEBNov 17, 2022 · A Cochrane review has found the strongest evidence yet that e-cigarettes, also known as ‘vapes’, help people to quit smoking better than traditional nicotine replacement therapies, such as patches and chewing gums.. New evidence published today in the Cochrane Library finds high certainty evidence that people are more likely to stop …