Cryo-EM reveals first high-resolution structure of the dynein-dynactin complex bound to microtubules | MRC Laboratory of Molecular Biology
Cryo-EM reveals first high-resolution structure of the dynein-dynactin complex bound to microtubules | MRC Laboratory of Molecular Biology
Sep 7, 2022
mrclmb.ac.uk
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Using microscopy-based in vitro reconstitutions, Sabina Colombo, Thomas Surrey and colleagues (Centre for Genomic Regulation - CRG) show that NuMA is a mitotic dynein adaptor that binds and caps microtubule minus ends, explaining how dynein, NuMA, dynactin, and Lis1 focus microtubule minus ends at mitotic spindle poles. https://hubs.la/Q036cclJ0 | Journal of Cell Biology
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Microtubule Interactions with the Cell Cortex Causing Nuclear Movements in Saccharomyces cerevisiae, The Journal of Cell Biology | DeepDyve
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A novel Q93H missense mutation in DCTN1 caused distal hereditary motor neuropathy type 7B and Perry syndrome from a Chinese family - Neurological Sciences
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wikimedia.org
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