📚 Difference Between Prokaryotic and Eukaryotic DNA Replication 🧬 🔹 Prokaryotic DNA Replication 1️⃣ Takes place in the cytoplasm 2️⃣ Single origin of replication (Monoreplicon) 3️⃣ Origin formed of ~100–200 nucleotides 4️⃣ Two replication forks, bidirectional 5️⃣ One replicon per chromosome 6️⃣ DNA Polymerase I & III involved 7️⃣ DNA gyrase required 8️⃣ Okazaki fragments: Large (1000–2000 nucleotides) 9️⃣ Fast process (~2000 nucleotides/sec) 🔟 DNA is circular & double-stranded 🔹 Eukaryotic